Perennial weeds in grain and forage crops used to be a major challenge faced by many of our producers. We know this is true because the older literature and extension bulletins highlighted the difficulty of controlling weeds like Canada thistle, quackgrass and field bindweed and many of us do not need publications to tell us this: we have lived in the era when perennial weeds were a real management challenge. Life has changed dramatically in the past 28 years and in this presentation I will cover the changes I’ve seen in perennial weed management. For each species presented, I will mention unique biological features, the research we have done and give the principal findings and the most effective management system.