The soybean cyst nematode (SCN; Heterodera glycines) and brown stem rot (BSR) fungus (Phialophora gregata) are serious pests of soybean, occurring over a range of soil types and soil pH. Often found in the same field, management strategies implemented to control one pathogen may in fact exacerbate damage caused by the other. As soybean acreage has increased, the duration between soybean crops has decreased in crop rotation schemes, thus also increasing the frequency of detecting dually infected fields. Control of each pathogen is directed at variety selection and crop rotation, and is refined further by matching variety selection with choice of herbicides and tillage practices.