The mission of APHIS-PPQ is to safeguard agriculture and natural resources from the risks associated with the entry, establishment, or spread of animal and plant pests and noxious weeds. One of our main emphases is to monitor potential pests for their presence within the nation’s borders. In Wisconsin, APHIS-PPQ is concerned with a wide variety of pests that threaten crops and natural resources. My presentation will highlight several of these pests. Two plant diseases, soybean rust and Ralstonia pose a major threat to several agricultural crops and are included in the Agricultural Bioterrorism Protection Act of 2002. Information on emerald ash borer, an insect pest of ash trees, and giant hogweed, an invasive weed, will also be presented.