Many biennial and perennial weeds seem to appear first in non-disturbed sites like roadsides. Such is the case of the biennial teasel (Dipsacus spp.) and the perennial leafy spurge (Euphorbia esula L.). Teasel is a new arrival and is appearing in several areas of southern Wisconsin. Leafy spurge has been here for decades, is found in many areas of Wisconsin and is invading new areas more rapidly than in the past. In this paper, I will describe the concern, give the plants’ key characteristics, review their biology, and discuss the management practices to control them.